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P-MS10

MOTS-C

4.9

(238)

Mots-c (mitochondrially derived peptide) is a 16-amino acid peptide encoded within the mitochondrial 12s ribosomal rna gene. Research applications include investigations into metabolic regulation, insulin sensitivity, glucose homeostasis, mitochondrial function, and age-related metabolic disorders in experimental models.

Variant Strength

Clear

1 Bottle

$49.00

2 Bottles

$46.55 (5% off)

3+ Bottles

$45.33 (7% off)

Quantity

x

15 Apl Wed - 18 Apl Wed

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Latest

99.8 %

PURITY

Variant

Mots-C 10 mg

Lot #

MS10-2603-02

Labeled

10 mg

Actual

9.3 mg

Tested

3/30/2026

Compound Information

Technical specifications

MOLECULAR PROFILE

What Is MOTS-c?

Type Mitochondrial-derived peptide

Amino Acids 16

Sequence MRWQEMGYIFYPRKLR

Molecular Weight 2,174.6 g/mol

Formula C101H152N28O22S2

Encoded in 12S rRNA (mtDNA)

STORAGE REQUIREMENTS

Stability Information

Extremely temperature sensitive Store frozen until use Reconstitute immediately before injection

Lyophilized (powder) -20°C ( stable long-term )

Reconstituted 2-8°C ( use immediately )

Room temperature Degrades 85-90% in 2-3 hrs

Sources & References

Peer reviewed research

CELL METABOLISM

The Mitochondrial-Derived Peptide MOTS-c Promotes Metabolic Homeostasis and Reduces Obesity and Insulin Resistance

2015 • DOI: 10.1016/j.cmet.2015.02.009 • PMID: 25738459

Lee C, Zeng J, Drew BG et al.

NATURE COMMUNICATIONS

MOTS-c is an exercise-induced mitochondrial-encoded regulator of age-dependent physical decline and muscle homeostasis

2021 • DOI: 10.1038/s41467-020-20790-0

Reynolds JC, Lai RW, Woodhead JST et al.

ALZHEIMER'S DRUG DISCOVERY FOUNDATION

MOTS-c Cognitive Vitality Report

ADDF Aging and Alzheimer’s Prevention Program

ALZHEIMER'S DRUG DISCOVERY FOUNDATION

MOTS-c Cognitive Vitality Report

2015 • DOI: 10.1111/acel.12389 • PMID: 26289118

Fuku N, Pareja-Galeano H, Zempo H et al.

PHYSIOL REP

The mitochondrial-derived peptide MOTS-c is a regulator of plasma metabolites and enhances insulin sensitivity

2019 • PMID: 31293078

Kim S-J, Miller B, Mehta HH et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mitochondria related peptide MOTS-c suppresses ovariectomy-induced bone loss via AMPK activation

2016

Ming W, Lu G, Xin S et al.

PEDIATRIC DIABETES

Circulating MOTS-c levels are decreased in obese male children and adolescents and associated with insulin resistance

2018

Du C, Zhang C, Wu W et al.

CLINICALTRIALS.GOV

Study of CB4211 in Patients With Nonalcoholic Fatty Liver Disease (NAFLD) and Obesity

2019

CohBar, Inc.

IMPORTANT RESEARCH NOTICE

Not for human consumption. This product is sold exclusively for research and educational purposes. It is not intended to diagnose, treat, cure, or prevent any disease.

All clinical trial data and research findings presented on this page are sourced from peer-reviewed journals and official publications. They are provided for educational reference only and should not be interpreted as medical advice or product claims.

By purchasing this product, you confirm that you are a qualified researcher and will use it in accordance with all applicable laws and regulations.

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