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BT10

TB-500

4.9

(198)

Tb-500 is a synthetic fragment of thymosin beta-4 for research into cellular repair and tissue regeneration. Research applications include investigations into cellular migration, tissue regeneration, wound healing, and angiogenesis in experimental models.

Variant Strength

Clear

1 Bottle

$84.00

2 Bottles

$79.80 (5% off)

3+ Bottles

$77.70 (7% off)

Quantity

x

15 Apl Wed - 18 Apl Wed

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Latest

99.7 %

PURITY

Variant

TB-500 10 mg

Lot #

TB10-2603-02

Labeled

10 mg

Actual

14.7 mg

Tested

3/30/2026

Compound Information

Technical specifications

MOLECULAR PROFILE

What Is TB-500?

Type Endogenous peptide/synthetic analog

CAS Number 77591-33-4

Molecular Weight 4,963 Da

Amino Acids 43

Active Region Ac-SDKP (N-terminal)

Key Sequence 17LKKTET22 (actin binding)

STORAGE REQUIREMENTS

Stability Information

Protect from light Store desiccated Sterile handling

❄️ Lyophilized (powder) -20°C ( stable long-term )

💉 Reconstituted 2-8°C ( use within 14-30 days )

Avoid Repeated freeze-thaw cycles

Sources & References

Peer reviewed research

EXPERT OPINION ON BIOLOGICAL THERAPY

Thymosin β4: a multi-functional regenerative peptide. Basic properties and clinical applications

2012 • DOI: 10.1517/14712598.2012.634793 • PMID: 22074294

Goldstein AL, Hannappel E, Sosne G, Kleinman HK

ANNALS OF THE NEW YORK ACADEMY OF SCIENCES

A randomized, placebo-controlled, single and multiple dose study of intravenous thymosin beta4 in healthy volunteers

2010 • DOI: 10.1111/j.1749-6632.2010.05474.x • PMID: 20536472

Ruff D, Crockford D, Girardi G, Zhang Y

JOURNAL OF THE NEUROLOGICAL SCIENCES

A Dose Response Study of Thymosin β4 for the Treatment of Acute Stroke

2014 • DOI: 10.1016/j.jns.2014.07.006 • PMID: 25060418

Morris DC, Cui Y, Cheung WL, Lu M, Zhang L, Zhang ZG, Chopp M

JOURNAL OF INVESTIGATIVE DERMATOLOGY

Thymosin beta4 accelerates wound healing

1999 • DOI: 10.1046/j.1523-1747.1999.00708.x • PMID: 10469335

Malinda KM, Sidhu GS, Mani H, Banaudha K, Maheshwari RK, Goldstein AL, Kleinman HK

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (PMC)

Progress on the Function and Application of Thymosin β4

2021 • DOI: 10.3390/ijms222413136

Xing Y, et al.

NATURE

Thymosin beta4 activates integrin-linked kinase and promotes cardiac cell migration, survival and cardiac repair

2004 • DOI: 10.1038/nature03000 • PMID: 15565145

Bock-Marquette I, Saxena A, White MD, Dimaio JM, Srivastava D

CLINICAL OPHTHALMOLOGY

Thymosin beta 4 ophthalmic solution for dry eye: a randomized, placebo-controlled, Phase II clinical trial

2015 • DOI: 10.2147/OPTH.S80954 • PMID: 26056426

Sosne G, Ousler GW

NEUROSCIENCE

Thymosin beta4 improves functional neurological outcome in a rat model of embolic stroke

2010 • DOI: 10.1016/j.neuroscience.2010.05.017 • PMID: 20627173

Morris DC, Chopp M, Zhang L, Lu M, Zhang ZG

JOURNAL OF NEUROSURGERY

Treatment of traumatic brain injury with thymosin beta4 in rats

2010 • DOI: 10.3171/2010.4.JNS10118 • PMID: 20486893

Xiong Y, Mahmood A, Meng Y, Zhang Y, Zhang ZG, Morris DC, Chopp M

NATURE

Thymosin beta4 induces adult epicardial progenitor mobilization and neovascularization

2007 • DOI: 10.1038/nature05383 • PMID: 17108969

Smart N, Risebro CA, Melville AA, Moses K, Schwartz RJ, Chien KR, Riley PR

IMPORTANT RESEARCH NOTICE

Not for human consumption. This product is sold exclusively for research and educational purposes. It is not intended to diagnose, treat, cure, or prevent any disease.

All clinical trial data and research findings presented on this page are sourced from peer-reviewed journals and official publications. They are provided for educational reference only and should not be interpreted as medical advice or product claims.

By purchasing this product, you confirm that you are a qualified researcher and will use it in accordance with all applicable laws and regulations.

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