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XA10

Semax

4.8

(464)

Chemical Formula: C33H50N8O10S
Molar Mass: 750.9 g/mol
Semax is a synthetic heptapeptide analog of adrenocorticotropic hormone (acth) for research into cognitive function and neuroprotection. Research applications include investigations into memory enhancement, neuroprotective effects, cognitive function, and neurotrophic factor modulation in experimental models.
1 Bottle
$49.00
2 Bottles
$46.55 (5% off)
3+ Bottles
$45.33 (7% off)
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COA Documentation

Every batch includes an in-depth Certificate of Analysis with full HPLC chromatograms, mass spectrometry profiles, synthesis records, and validated purity results to ensure total transparency.

Latest

99.8 %

PURITY

Variant

Semax 10 mg

Lot #

SX10-2603-02

Labeled

10 mg

Actual

7.7 mg

Tested

7.7 mg

View COA Document

Compound Information

Technical specifications

What Is Semax? MOLECULAR PROFILE

What Is Semax?

Synthetic heptapeptide analog of ACTH (4-10) with C-terminal Pro-Gly-Pro extension for enhanced stability

Heptapeptide ACTH Analog
Type Synthetic heptapeptide
CAS Number 80714-61-0
Molecular Formula C37H51N9O10S
Molecular Weight 813.9 g/mol
Amino Acids 7 residues
Sequence Met-Glu-His-Phe-Pro-Gly-Pro
Stability Information STORAGE REQUIREMENTS

Stability Information

Light sensitive Temperature sensitive
Lyophilized (powder) -20°C ( protect from light )
Reconstituted 2-8°C ( use within 4 weeks )
Nasal spray 2-8°C ( 30 days after opening )
Regulatory Information DEVELOPMENT STATUS

Regulatory Information

Developed at the Institute of Molecular Genetics of the Russian Academy of Sciences

Developer Russian Academy of Sciences
Approval Russia (1990s)
Indications Stroke, cognitive impairment
Formulations 0.1% and 1% nasal spray
US Status Not FDA-approved
Related Peptide Selank (tuftsin analog)

Sources & References

Peer reviewed research

BRAIN RESEARCH

Semax, an analog of ACTH(4-10) with cognitive effects, regulates BDNF and trkB expression in the rat hippocampus

2006 • DOI: 10.1016/j.brainres.2006.07.108 • PMID: 16996037

Dolotov OV, Karpenko EA, Inozemtseva LS, et al.

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BMC GENOMICS

The peptide semax affects the expression of genes related to the immune and vascular systems in rat brain focal ischemia

2014 • DOI: 10.1186/1471-2164-15-228 • PMID: 24661656

Medvedeva EV, Dmitrieva VG, Povarova OV, et al.

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ZHURNAL NEVROLOGII I PSIKHIATRII IMENI S.S. KORSAKOVA

The efficacy of semax in the treatment of patients at different stages of ischemic stroke

2018 • PMID: 29798983

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JOURNAL OF MOLECULAR NEUROSCIENCE

Comparison of the temporary dynamics of NGF and BDNF gene expression in rat hippocampus, frontal cortex, and retina under Semax action

2010 • DOI: 10.1007/s12031-009-9270-z • PMID: 19662538

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INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Novel Insights into the Protective Properties of ACTH(4-7)PGP (Semax) Peptide at the Molecular Level

2020 • PMID: 32575851

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ALZHEIMER'S DRUG DISCOVERY FOUNDATION

Semax - Cognitive Vitality For Researchers

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PUBCHEM DATABASE

Semax - Compound Summary (CID 9811102)

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IMPORTANT RESEARCH NOTICE

Not for human consumption. This product is sold exclusively for research and educational purposes. It is not intended to diagnose, treat, cure, or prevent any disease.

All clinical trial data and research findings presented on this page are sourced from peer-reviewed journals and official publications. They are provided for educational reference only and should not be interpreted as medical advice or product claims.

By purchasing this product, you confirm that you are a qualified researcher and will use it in accordance with all applicable laws and regulations.

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