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PT-141

PT-141 (bremelanotide) is a synthetic peptide agonist of melanocortin receptors MC3R and MC4R, derived from the endogenous alpha-melanocyte-stimulating hormone (α-MSH). Research applications include investigations into central mechanisms of sexual arousal, autonomic pathway modulation, and melanocortin receptor signaling in experimental models.

Variant Strength

Clear

1 Bottle

$49.99

2 Bottles

$47.49 (5% off)

3+ Bottles

$46.24 (7% off)

Products arrive in lyophilized powder form for optimal stability.

Quantity

x

15 Apl Wed - 18 Apl Wed

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Latest

99.9 %

PURITY

Variant

Melanotan II 10 mg

Lot #

ML10-2603-02

Labeled

10 mg

Actual

10.2 mg

Tested

3/30/2026

Latest

99.1 %

PURITY/POTENCY/ENDOTOXIN/HEAVY METALS/STERILITY

Variant

PT-141 10 mg

Lot #

PT10-2608-01

Labeled

10 mg

Actual

10.18 mg

Tested

8/03/2026

View COA Document →

Compound Information

Chemical and structural properties

MOLECULAR PROFILE

PT-141 Structure

Synthetic cyclic heptapeptide analog of α-MSH

Cyclic Heptapeptide α-MSH Analog

CAS Number 189691-06-3

Molecular Formula C50H68N14O10

Molecular Weight 1025.2 g/mol

Sequence Ac-Nle-c[Asp-His-D-Phe-Arg-Trp-Lys]-OH

Structure Cyclic heptapeptide

RECEPTOR BINDING

Melanocortin Receptor Affinity

Non-selective melanocortin receptor agonist

FDA Approved

MC1R High affinity (pigmentation)

MC3R Moderate (metabolism)

MC4R High affinity (sexual function)

MC5R Moderate (exocrine)

PHYSICAL PROPERTIES

Formulation Characteristics

Handling and storage requirements

Appearance White lyophilized powder

Solubility Soluble in water, saline

Storage 2-8°C (refrigerated)

Reconstituted stability 30 days refrigerated

Sources & References

Peer reviewed research

OBSTETRICS & GYNECOLOGY

Bremelanotide for the Treatment of Hypoactive Sexual Desire Disorder: Two Randomized Phase 3 Trials

2019 • DOI: 10.1097/AOG.0000000000003500 • PMID: 31599840

Kingsberg SA, Clayton AH, Portman D, et al.

INTERNATIONAL JOURNAL OF IMPOTENCE RESEARCH

PT-141: a melanocortin agonist for the treatment of sexual dysfunction

2004 • PMID: 12851303

Diamond LE, Earle DC, Rosen RC, et al.

JOURNAL OF SEXUAL MEDICINE

An effect on the subjective sexual response in premenopausal women with sexual arousal disorder by bremelanotide (PT-141), a melanocortin receptor agonist

2006 • DOI: 10.1111/j.1743-6109.2006.00268.x • PMID: 16839319

Diamond LE, Earle DC, Heiman JR, et al.

JOURNAL OF WOMEN'S HEALTH

Reported Event Profile of Bremelanotide Across the Clinical Development Program

2022 • DOI: 10.1089/jwh.2021.0191

FDA

Vyleesi (bremelanotide) Prescribing Information

2019

MEDICINA (KAUNAS)

Bremelanotide for Treatment of Female Hypoactive Sexual Desire Disorder

2022 • PMID: 35056399

PUBCHEM DATABASE

Bremelanotide - Compound Summary (CID 9941379)

IMPORTANT RESEARCH NOTICE

Not for human consumption. This product is sold exclusively for research and educational purposes. It is not intended to diagnose, treat, cure, or prevent any disease.

All clinical trial data and research findings presented on this page are sourced from peer-reviewed journals and official publications. They are provided for educational reference only and should not be interpreted as medical advice or product claims.

By purchasing this product, you confirm that you are a qualified researcher and will use it in accordance with all applicable laws and regulations.

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